integrin αv gene expression knockdown inhibition (Santa Cruz Biotechnology)
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Integrin αv Gene Expression Knockdown Inhibition, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 86/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/integrin αv gene expression knockdown inhibition/product/Santa Cruz Biotechnology
Average 86 stars, based on 4 article reviews
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1) Product Images from "Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): a second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells"
Article Title: Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): a second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells
Journal: Toxicon : official journal of the International Society on Toxinology
doi: 10.1016/j.toxicon.2016.04.038
Figure Legend Snippet: αvβ3 integrin cell surface expression on untransduced, scrambled shRNA, and αv stable knocked down SK-Mel-28 cells. p<0.001 (***). αvβ5 integrin expression was not examined since we demonstrated that SK-Mel-28 cells do not express the β5 subunit (Seoane et al. 2010).
Techniques Used: Expressing, shRNA
Figure Legend Snippet: r-Moj-DL, r-Moj-DM, and r-Moj-DN peptides induced apoptosis of SK-Mel-28 cells by binding to the αv integrin. p=0.05 (*), p=0.01 (**), p<0.001 (***).
Techniques Used: Binding Assay
Figure Legend Snippet: All r-Moj-D_ mutant peptides inhibited proliferation of SK-Mel-28 cells by binding to the αv integrin. The scrambled shRNA control treated cells are not shown, since these cells grew at much slower rate than untransduced or αv knocked down cells.
Techniques Used: Mutagenesis, Binding Assay, shRNA